Scope

"Post-translational modifications represent a highly versatile and dynamic mechanism to expand the functional diversity of the proteome" "Dr. Jennifer Doudna, Nobel Prize Winner, Chemistry 2020"

Protein function is often regulated by complex interplay of Post-translationally modification shaping their role in cellular processes Sir Francis Arnold, "Nobel Prize Winner, Chemistry 2018"

Post-translationally modified proteins with complex eukaryotic modifications, such as glycosylation, phosphorylation, and disulfide bond formation, are characteristic of Insect cellular machinery. This process can be performed using Baculovirus Expression System modifications that allow the proteins to adopt a conformation suitable for studying their biological activity, structural properties, and stability—key factors for developing biopharmaceutical proteins in an efficient and scalable way.

The workshop will equip students with hands-on technical skills that can be applied in their PhD projects and future careers. The expertise gained in insect cell-based systems will be valuable in areas such as Drug discovery, Designing drugs, Structural analysis, and understanding precise functional roles, leading to well-recognized studies. The Baculovirus (Insect) expression vector system is the preferred choice for expressing proteins over bacterial systems.

Selection Criteria