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Publications

  1. Sharma A., Dsilva G.J., Deshpande G. # and Galande S. # 2024. Exploring the Versatility of Zygotic Genome Regulators: A Comparative and Functional Analysis. Cell Reports 43(9): 1-15. https://doi.org/10.1016/j.celrep.2024.114680.

  2. Dsilva G J and Galande S. # 2024. From Sequence to Consequence: Deciphering the Complex cis-regulatory landscape. J Biosciences 49:46. DOI: 10.1007/s12038-024-00431-0.

  3. Tripathi S.*, Gupta E.*, Galande, S. # 2024. Statins as anti-tumor agents: A paradigm for repurposed drugs. Cancer Reports 7:e2078. https://doi.org/10.1002/cnr2.2078.

  4. Suresh V. *, Muralidharan, B. *, Pradhan, S. J. *, Bose, M., D’Souza, L., Parichha, A., Reddy, P. C., Galande, S.# and Tole, S.# 2023. Regulation of chromatin accessibility and gene expression in the developing hippocampal primordium by LIM-HD transcription factor LHX2. PLoS Genetics 19(8):e1010874.doi: 10.1371/journal.pgen.1010874.

  5. Gungi, A., Saha, S., Pal, M. and Galande, S. #, 2023. H4K20me1 plays a dual role in transcriptional regulation of regeneration and axis patterning in Hydra. Life Science Alliance, 6(5).

  6. Khare, S.P. *, Madhok, A. *, Patta, I., Sukla, K.K., Wagh, V.V., Kunte, P.S., Raut, D., Bhat, D., Kumaran, K., Fall, C. and Tatu, U., Chandak G.R., Yajnik C. S. #, Galande, S. # 2023. Differential expression of genes influencing mitotic processes in cord blood mononuclear cells after a pre-conceptional micronutrient-based randomised controlled trial: Pune Rural Intervention in Young Adolescents (PRIYA). Journal of Developmental Origins of Health and Disease, 14: 437–448. doi: 10.1017/S204017442200068X

  7. Pradhan SJ, Reddy PC, Smutny M, Sharma A, Sako K, Oak MS, Shah R, Pal M, Deshpande O, Dsilva G, Tang Y, Mishra R, Deshpande G, Giraldez AJ, Sonawane M, Heisenberg CP#, Galande S#. (2021) Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis. Nat Commun. 12:6094. doi: 10.1038/s41467-021-26234-7. PMID: 34667153

  8. Shah R, Sharma A*, Kelkar A*, Sengupta K, and Galande S#. 2021. A novel cis regulatory element regulates human XIST in CTCF-dependent manner. Mol Cell Biol, 41(8):e0038220. doi: 10.1128/MCB.00382-20DOI: doi.org/10.1128/MCB.00382-20

  9.  Reddy, PC*, Gungi A*, Ubhe, S, and Galande S# (2020) Epigenomic landscape of enhancer elements during Hydra head organizer formation. Epigenetics and Chromatin Oct 12;13(1):43. doi: 10.1186/s13072-020-00364-6. PMID: 33046126

  10. Patta I, Madhok A, Khare SP, Gottimukkala KP, Verma A, Giri S, Dandewad V, Seshadri V, Lal G, Misra-Sen J and Galande S# (2020), Dynamic regulation of chromatin organizer SATB1 via TCR induced alternative promoter switch during T-cell development. Nucleic Acids Res 48:5873-5890. PMID: 32392347.

  1. Dubey S, Gupta H and Gupta A* (2024) Autoacetylation-mediated phase separation of TIP60 is critical for its functions.  eLife 13 (https://doi.org/10.7554/eLife.93418.1), RP93418 

  2. Jaiswal B, Agarwal A and Gupta A* (2022) Lysine Acetyltransferases and Their Role in AR Signaling and Prostate Cancer. Frontiers in Endocrinology 13:886594 

  3. Dubey S, Jaiswal B and Gupta A* (2022) TIP60 acts as a regulator of genes involved in filopodia formation and cell migration during wound healing. Journal of Biological Chemistry 298(7):102015. 

  4. Sen U, Nayak A, Khurana J, Sharma D and Gupta A* (2020) Inhibition of PfMYST Histone Acetyltransferase Activity Blocks Plasmodium falciparum Growth and Survival. Antimicrobial Agents and Chemotherapy 65(1):e00953-20. 

  5. Sen U, Saxena H, Khurana J, Nayak A and Gupta A* (2018) Plasmodium falciparum RUVBL3 protein: a novel DNA modifying enzyme and an interacting partner of essential HAT protein MYST. Scientific Reports 8(1):10917 

  6. Jaiswal B and Gupta A* (2018) Modulation of nuclear receptor function by chromatin modifying factor TIP60. Endocrinology 159(5):2199-2215.)

  7. Bakshi K, Ranjitha B, Dubey S, Jagannadham J, Jaiswal B, Gupta A* (2017) Novel complex of HAT protein TIP60 and nuclear receptor PXR promotes cell migration and adhesion. Scientific Reports 7(1):3635. (*Corresponding author)

  8. Jha S*, Gupta A*, Dar A and Dutta A (2013) RVBs are required for assembling a functional TIP60 complex. Molecular and Cellular Biology 33(6):1164-74. 

  9. Gupta A, Jha S, Engel D, Ornelles D and Dutta A (2013) Tip60 Degradation by Adenovirus Relieves Transcriptional Repression of Viral Transcriptional Activator EIA. Oncogene 32(42):5017-25.

  1. Rajkumar MS, Tembhare K, Garg R, Jain M. Genome-wide mapping of DNase I hypersensitive sites revealed differential chromatin accessibility and regulatory DNA elements under drought stress in rice cultivars. Plant Journal. 2024;  doi: 10.1111/tpj.16864.

  2. Singh S, Singh S, Gupta K, et al. Genome-Wide Identification of G-Quadruplex forming regions in Arabidopsis: Unraveling the Role of Pif like Helicase (AtPLH1) in Gene Regulation and Stress Response. bioRxiv; 2024. DOI: 10.1101/2024.03.11.584348.

  3. Singh V, Gupta K, Singh S, Jain M, Garg R. Unravelling the molecular mechanism underlying drought stress response in chickpea via integrated multi-omics analysis. Frontiers in Plant Sciences 2023; 14:1156606. doi: 10.3389/fpls.2023.1156606.

  4. Gupta K, Garg R. Unravelling Differential DNA Methylation Patterns in Genotype Dependent Manner under Salinity Stress Response in Chickpea. Int J Mol Sci. 2023; 24(3):1863. doi: 10.3390/ijms24031863.

  5. Jain M, Garg R. Enhancers as potential targets for engineering salinity stress tolerance in crop plants. Physiologia Plantarum, 2021;173(4):1382-1391. doi: 10.1111/ppl.13421.

  6. Jain M, Bansal J, Rajkumar MS, Garg R. An integrated transcriptome mapping the regulatory network of coding and long non-coding RNAs provides a genomics resource in chickpea. Communications Biology, 2022; 5(1):1106. doi: 10.1038/s42003-022-04083-4.

  1. Channakkar, A.S., D’Souza, L., Kumar, A., Kalia, K., Prabhu, S., Phalnikar, K., Reddy, P.C., and Muralidharan, B. (2024). LSD1 Regulates Neurogenesis in Human Neural Stem Cells Through the Repression of Human-Enriched Extracellular Matrix and Cell Adhesion Genes. Stem Cells 42, 128-145.

  2. Suresh, V., Muralidharan, B., Pradhan, S.J., Bose, M., D’Souza, L., Parichha, A., Reddy, P.C., Galande, S., and Tole, S. (2023). Regulation of chromatin accessibility and gene expression in the developing hippocampal primordium by LIM-HD transcription factor LHX2. PLoS Genetics 19, e1010874.

  3. Patil, S., Mishra, V.S., Reddy, P.C.*, and Lochab, B.* (2023). Multifunctional Multicomponent Highly Biocompatible pH-Responsive Iron-Oxide Embedded Nanodiamond Cargo for Artesunate to Inhibit Cancer Growth. ACS Materials Letters 5, 336-340.

  4. Mishra, V.S., Patil, S., Reddy, P.C.*, and Lochab, B.* (2022). Combinatorial delivery of CPI444 and vatalanib loaded on PEGylated graphene oxide as an effective nanoformulation to target glioblastoma multiforme: In vitro evaluation. Frontiers in Oncology 12, 953098.

  5. Patil, S., Mishra, V.S., Yadav, N., Reddy, P.C., and Lochab, B. (2022). Dendrimer-functionalized nanodiamonds as safe and efficient drug carriers for cancer therapy: nucleus penetrating nanoparticles. ACS Applied Bio Materials 5, 3438-3451.

  6. Pillai, A., Gungi, A., Reddy, P.C.*, and Galande, S.* (2021). Epigenetic regulation in hydra: Conserved and divergent roles. Frontiers in Cell and Developmental Biology 9, 663208.

  7. Pradhan, S.J., Reddy, P.C., Smutny, M., Sharma, A., Sako, K., Oak, M.S., Shah, R., Pal, M., Deshpande, O., and Dsilva, G. (2021). Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis. Nature Communications 12, 6094.

  8. Reddy, P.C.#, Gungi, A.#, Ubhe, S., and Galande, S. (2020a). Epigenomic landscape of enhancer elements during Hydra head organizer formation. Epigenetics & Chromatin 13, 1-16.

  9. Reddy, P.C., Pradhan, S.J., Karmodiya, K., and Galande, S. (2020b). Origin of RNA Polymerase II pause in eumetazoans: Insights from Hydra. Journal of biosciences 45, 8.

  10. Reddy, P.C., Gungi, A., Ubhe, S., Pradhan, S.J., Kolte, A., and Galande, S. (2019a). Molecular signature of an ancient organizer regulated by Wnt/β-catenin signalling during primary body axis patterning in Hydra. Communications biology 2, 434.

  11. Reddy, P.C.*, Gungi, A., and Unni, M. (2019b). Cellular and molecular mechanisms of Hydra regeneration. Evo-Devo: Non-model Species in Cell and Developmental Biology, 259-290.

  12. Reddy, P.C., Ubhe, S., Sirwani, N., Lohokare, R., and Galande, S. (2017). Rapid divergence of histones in Hydrozoa (Cnidaria) and evolution of a novel histone involved in DNA damage response in hydra. Zoology 123, 53-63.

  1. Pawar K, Kawamura T, Kirino Y. The tRNAVal half: A strong endogenous Toll-like receptor 7 ligand with a 5'-terminal universal sequence signature. PNAS. 121(19):e2319569121 (2024)

  2. Pawar K, Shigematsu M. Sharbati, Kirino Y. Infection-induced 5'-half molecules of tRNAHisGUG activate Toll-like receptor 7. PLOS Biology. 18(12):e3000982. (2020)

  3. Pawar K, Shigematsu M, Loher P, Honda S, Rigoutsos I, Kirino Y. Exploration of CCA-added RNAs revealed the expression of mitochondrial non-coding RNAs regulated by CCA-adding enzyme. RNA Biology 16(12):1817-1825. (2019)

  4. Pawar K, Hanisch C, Eliseo Palma Vera S, Einspanier R, Sharbati S. Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy. Scientific Reports. 6:19416 (2016)

  5. Pawar K, Sharbati J, Einspanier R, Sharbati S. Mycobacterium bovis BCG Interferes with miR-3619-5p Control of Cathepsin S in the Process of Autophagy. Front Cell Infect Microbiol. 6:27 (2016)