Faculty at School of Natural Sciences
Kamalesh Kumari
Ramalingaswami Re-entry Fellow
School of Natural Sciences
Contact Information
- Email: [email protected]
- 2012-2017- Ph.D. in Biology. National Centre for Biological Sciences (NCBS-TIFR), Bangalore, India (Advisor: Prof. Raghu Padinjat & Prof. Shobhona Sharma ). Research Areas: Developmental cell biology, Lipid signaling, Membrane trafficking.
- 2008-2012- Research fellow in Biology. Tata Institute of Fundamental Research (TIFR), Mumbai. (Supervisor: Dr. V. Sriram.) Research Areas: Developmental cell biology, Mitochondrial remodeling during cell death.
- 2006-2008- M.Sc. in Genetics. University of Delhi, South campus, New Delhi, India.
- 2003-2006- B.Sc. (Hons) in Biomedical Sciences. Acharya Narendra Dev College, University of Delhi, Delhi, India
- 2017-2024- Postdoctoral Fellow. Weizmann Institute of Science (WIS), Rehovot, Israel. (Advisors: Prof. Ben-Zion Shilo & Prof. Ori Avinoam). Research Areas: Cell and developmental Biology, Biophysics, Cellular structural biology.
- Membrane remodelling during cellular exocrine secretion: Investigating how cells preserve surface integrity under continuous vesicle fusion and recycling events.
- Membrane biophysics and cell biology of membrane reservoirs: Understanding physicochemical properties of membranes in maintaining cellular membrane reservoirs.
- Lipid signalling regulating membrane curvature, trafficking, and cellular homeostasis.
- Live Imaging of organelle dynamics to quantify organelle function and behaviour.
- Correlative (Light and Electron) Microscopy, high-throughput cellular electron microscopy data acquisition and cellular electron tomography for detailed structural-functional studies.
- 2024- Ramalingaswamy Re-entry Fellowship, Department of Biotechnology (DBT), India
- 2021- Israeli Society for Developmental Biology (IsSDB) award for ‘cool paper’ of 2021, for my publication- Kamalesh, K. et al. Dev. Cell, 2021, describing a new pathway of exocytosis.
- 2018- American Society for Cell Biology (ASCB) travel award.
- 2018- Dean’s fellowship award for postdoctoral researchers, Weizmann Institute of Science, Rehovot Israel.
- 2015- Department of Biotechnology, Government of India (DBT-CTEP) travel award, for attending international conferences.
- 2015- NCBS annual meeting themed ‘Biology across scales’ best poster award and travel grant, for attending international conferences.
- 2015- American Society for Cell Biology (ASCB) travel award.
- 2008- CSIR-UCG National Eligibility Test (NET) qualification and fellowship to pursue research and lectureship in India.
- 2008- South Campus endorsement scholarship for toppers in master’s in science programs, University of Delhi, New Delhi, India.
- 2007- Indian Academy of Sciences (IAS), Indian Nation Sciences Academy (INSA) and National Academy of sciences (NASI)- summer research fellowship for young enthusiasts in research.
- 2006- Monsanto’s postgraduate award and scholarship for securing the top position in all India entrance exam for Master in Genetics program, University of Delhi, New Delhi, India.
- American Society for Cell Biology
- Kamalesh, K., Segal, D., Avinoam, O., Schejter, E.D., and Shilo, B.-Z. Structured RhoGEF recruitment drives myosin II organization on large exocytotic vesicles. J Cell Sci. 2024 Jul 1;137(13):jcs261944.
- Exocytosis by vesicle crumpling maintains apical membrane homeostasis during exocrine secretion. K. Kamalesh, N. Scher, T. Biton, E. D. Schejter, B. Z. Shilo, O. Avinoam, Dev. Cell. 56, 1603-1616 (2021). DOI: 10.1016/j.devcel.2021.05.004
- Highlighted article: A mechanochemical mechanism couples exocrine secretion to endocytic membrane retrieval. V. Haucke, Dev. Cell. 56, 1557-1559 (2021).
- Highlighted by F1000 Biology.
- Selected for cover of the of Dev Cell journal.
- Phosphatidylinositol 5-phosphate 4-kinase regulates early endosomal dynamics during clathrin-mediated endocytosis. K. Kamalesh, D. Trivedi, S. Toscano, S. Sharma, S. Kolay, P. Raghu, J. Cell Sci. 130 (2017). DOI: 10.1242/jcs.202259
- A dPIP5K Dependent Pool of Phosphatidylinositol 4,5-bisphosphate (PIP2) is Required for G-Protein Coupled Signal Transduction in Drosophila Photoreceptors. P. Chakrabarti, S. Kolay, S. Yadav, K. Kumari, A. Nair, D. Trivedi, P. Raghu, PLoS Genet. 11, 1004948 (2015). DOI: 10.1371/journal.pgen.1004948
- 2023- The Indian Drosophila Research Conference (InDRC), Trivandrum, India (selected talk and oral presentation award)
- 2023- Young Investigator’s meeting (YIM), Ahmedabad, India (selected talk and poster).
- 2022- Research Group Leadership course for postdoctoral fellows by hfp consulting, WIS, Israel
- 2021- American Society for Cell Biology (ASCB), virtual meeting, USA (poster).
- 2021- Annual meeting of the Israeli Society for Developmental Biology, (invited talk for ‘Cool paper award), virtual meeting, WIS, Israel.
- 2021- National Post-Doctoral Symposia, virtual meeting, India (selected talk)
- 2021- Molecular Membrane Biology online conference in place of the GRC, virtual meeting (selected talk and poster).
- 2020- American Society for Cell Biology (ASCB), virtual meeting, USA (poster).
- 2020- EMBO | EMBL Symposium: Organoids: Modelling Organ Development and Disease in 3D Culture, virtual meeting.
- 2020- Morphogenesis 2020- mechanobiology online conference, NUS, Singapore, (poster).
- 2019- EMBO | Seeing is believing symposia, EMBL, Heidelberg, Germany, (poster)
- 2018- American Society for Cell Biology (ASCB) meeting, San Diego, USA (invited subgroup talk and poster).
- 2018- Annual meeting of the Israeli Society for Developmental Biology, Tel Aviv, Israel.
- 2017- JAX India seminars on Mouse genetics, Bangalore, India.
- 2016- Electron Tomography Workshop, NCBS, Bangalore, India
- 2015- American Society for Cell Biology (ASCB) meeting, San Diego, USA (poster).
- 2015- NCBS meeting ‘Biology across scales’, Bangalore, India. (Best poster award and travel grant award)
- 2015- Annual Meeting of NCBS Max Planck Lipid Centre, Bangalore, India, (poster).
- 2014- MBI Meeting on Electron microscopy, Frontiers in Bio-Imaging, Bangalore, India (poster)
- 2013- All India cell biology Conference, Bangalore, India, (poster).
- 2012- Inositide signaling in health and diseases meeting, Coorg, India, (poster)