1995 – 2000 PhD Biology. University of California, San Diego (Advisor: Dr. Vivek Malhotra)
1989 – 1993 B.S., Biological Sciences. University of California, Davis.
2018 – present Professor and Laboratory Director, IFOM-inStem Joint Research Laboratory, Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India
2015 – present Scientific Advisor, Aeon Biotherapeutics Inc. (Taiwan, ROC)
2013 – present Coordinator, Centre for Inflammation and Tissue Homeostasis, inStem.
2012 – 2018 Associate Professor and Laboratory Director, IFOM-inStem Joint Research Laboratory, Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India
2012 – 2014 Research Associate, Department of Bioengineering, Jacobs School of Engineering, University of California, San Diego
2011 – 2012 Adjunct Associate Professor, Division of Dermatology/Department of Medicine, University of California, San Diego
2006 – 2011 Adjunct Assistant Professor, Division of Dermatology/Department of Medicine. University of California, San Diego
2006 – 2012 UCSD Cell and Molecular Genetics Training Program
2005 – 2012 Member, UCSD/Moores Comprehensive Cancer Center
2004 – 2012 Assistant Professor, Section of Cell and Developmental Biology/Division of Biological Sciences. University of California, San Diego
2021 – 2024 PLoS Biology Academic Editor
2021 – present Member, Scientific Advisory Committee. Therapy Resistance and Stem Cell Biology Group, Advanced Centre for Treatment, Research, and Education in Cancer (ACTREC), Mumbai India
2012 American Society for Cell Biology MAC Travel Award
2012 Keystone Symposium Early Career Investigator Travel Award
2011 UC San Diego Academic Senate Travel Award
2009 - 2010 Hellman Faculty Fellow. Awarded to “faculty members at the Assistant Professor rank who exhibit the potential for great academic distinction”
2009 Chair of Epidermal Biology Session, Montagna Symposium
2008 – 2012 American Cancer Society Research Scholar
2007 – 2009 Ad hoc reviewer for NIH grants (ACTS Study Section)
2006 Visiting Professor, Instituto Butantan, Sao Paulo, Brazil
2006 – 2008 Research Career Development Award, Dermatology Foundation
2006 UC San Diego Academic Senate Travel Award
2001-2004 Helen Hay Whitney Postdoctoral Fellowship
2000-2001 Howard Hughes Medical Institute Postdoctoral Fellowship
1998 ASCB Predoctoral Travel Award
1997-1998 US Department of Education GAANN Fellowship
1995-1997 San Diego Fellowship
Rana, I., Kataria, S., Tan, T-L., Hajam, E.Y., Kashyap, D.K., Saha, D., Ajnabi, J., Paul, S., Jayappa, S., Ananthan, A.|S., Kumar, P., Zaarour, R.F., Haarshaadri, J., Kansagara, G., Rizvi, A., Zirmire, R.K., Badarinath, K., Khedkar, S.U., Chandra, Y., Samuel, R., George, R., Danda, D., Jacob, P.M., Dey, R., Dhandapany , P.S., He, Y-W., Varga, J., Varghese, S., Jamora, C. (2023) Mindin is essential for cutaneous fibrogenesis in a mouse model of systemic sclerosis. J of Investigative Dermatology143, 699-710.e10
Zaarour, R. F., Saha, D., Dey, R., Dutta, A., Kumar, P., Rana, I., Pulianmackal, A., Rizvi, A., Misra, N., Breton, L., and Jamora, C. (2022) The neuropeptide Substance P facilitates the transition from an inflammatory to proliferation phase-associated responses in dermal fibroblasts. Exp Dermatol31, 1188-1201
Sobecki, M., Chen, J., Krzywinska, E., Nagarajan, S., Fan, Z., Nelius, E., Monne Rodriguez, J. M., Seehusen, F., Hussein, A., Moschini, G., Hajam, E. Y., Kiran, R., Gotthardt, D., Debbache, J., Badoual, C., Sato, T., Isagawa, T., Takeda, N., Tanchot, C., Tartour, E., Weber, A., Werner, S., Loffing, J., Sommer, L., Sexl, V., Munz, C., Feghali-Bostwick, C., Pachera, E., Distler, O., Snedeker, J., Jamora, C., and Stockmann, C. (2022) Vaccination-based immunotherapy to target profibrotic cells in liver and lung. Cell Stem Cell29, 1459-1474 e1459
Hajam, E. Y., Panikulam, P., Chu, C. C., Jayaprakash, H., Majumdar, A., and Jamora, C. (2022) The expanding impact of T-regs in the skin. Front Immunol13, 983700
Bhatt, T., Dey, R., Hegde, A., Ketkar, A. A., Pulianmackal, A. J., Deb, A. P., Rampalli, S., and Jamora, C. (2022) Initiation of wound healing is regulated by the convergence of mechanical and epigenetic cues. PLoS Biol20, e3001777
Badarinath, K., Dam, B., Kataria, S., Zirmire, R. K., Dey, R., Kansagara, G., Ajnabi, J., Hegde, A., Singh, R., Masudi, T., Sambath, J., Sachithanandan, S. P., Kumar, P., Gulyani, A., He, Y. W., Krishna, S., and Jamora, C. (2022) Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin. Cell Rep40, 111390
Zaarour, R. F., Azakir, B., Hajam, E. Y., Nawafleh, H., Zeinelabdin, N. A., Engelsen, A. S. T., Thiery, J., Jamora, C., and Chouaib, S. (2021) Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival. Cancers (Basel)13
Saha, D., Thannimangalath, S., Budamakuntla, L., Loganathan, E., and Jamora, C. (2021) Hair Follicle Grafting Therapy Promotes Re-Emergence of Critical Skin Components in Chronic Nonhealing Wounds. JID Innov1, 100041
Rana, I., Badarinath, K., Zirmire, R. K., and Jamora, C. (2021) Isolation and Quantification of Mouse gammadeltaT-cells in vitro and in vivo. Bio Protoc11, e4148
Gund, R., Zirmire, R., J, H., Kansagara, G., and Jamora, C. (2021) Histological and Immunohistochemical Examination of Stem Cell Proliferation and Reepithelialization in the Wounded Skin. Bio Protoc11, e3894
Biswas, R., Banerjee, A., Lembo, S., Zhao, Z., Lakshmanan, V., Lim, R., Le, S., Nakasaki, M., Kutyavin, V., Wright, G., Palakodeti, D., Ross, R. S., Jamora, C., Vasioukhin, V., Jie, Y., and Raghavan, S. (2021) Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells. Dev Cell56, 761-780 e767
Bhatt, T., Bhosale, A., Bajantri, B., Mathapathi, M. S., Rizvi, A., Scita, G., Majumdar, A., and Jamora, C. (2019) Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8. Cell Rep29, 2546-2555 e2544
Badarinath, K., Dutta, A., Hegde, A., Pincha, N., Gund, R., and Jamora, C. (2019) Interactions Between Epidermal Keratinocytes, Dendritic Epidermal T-Cells, and Hair Follicle Stem Cells. Methods Mol Biol1879, 285-297
Pincha, N., Saha, D., Bhatt, T., Zirmire, R. K., and Jamora, C. (2018) Activation of Fibroblast Contractility via Cell-Cell Interactions and Soluble Signals. Bio Protoc8, e3021
Pincha, N., Hajam, E. Y., Badarinath, K., Batta, S. P. R., Masudi, T., Dey, R., Andreasen, P., Kawakami, T., Samuel, R., George, R., Danda, D., Jacob, P. M., and Jamora, C. (2018) PAI1 mediates fibroblast-mast cell interactions in skin fibrosis. J Clin Invest128, 1807-1819
Lee, P., Gund, R., Dutta, A., Pincha, N., Rana, I., Ghosh, S., Witherden, D., Kandyba, E., MacLeod, A., Kobielak, K., Havran, W. L., and Jamora, C. (2017) Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of gammadeltaT-cells. Elife6
Nakasaki, M., Hwang, Y., Xie, Y., Kataria, S., Gund, R., Hajam, E. Y., Samuel, R., George, R., Danda, D., M, J. P., Nakamura, T., Shen, Z., Briggs, S., Varghese, S., and Jamora, C. (2015) The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis. Nat Commun6, 8574
Lee, D. J., Du, F., Chen, S. W., Nakasaki, M., Rana, I., Shih, V. F. S., Hoffmann, A., and Jamora, C. (2015) Regulation and Function of the Caspase-1 in an Inflammatory Microenvironment. J Invest Dermatol135, 2012-2020
Ando, T., Matsumoto, K., Namiranian, S., Yamashita, H., Glatthorn, H., Kimura, M., Dolan, B. R., Lee, J. J., Galli, S. J., Kawakami, Y., Jamora, C., and Kawakami, T. (2015) Mast Cells Are Required for Full Expression of Allergen/SEB-Induced Skin Inflammation. J Invest Dermatol135, 925
Kim, J., Nakasaki, M., Todorova, D., Lake, B., Yuan, C. Y., Jamora, C., and Xu, Y. (2014) p53 Induces skin aging by depleting Blimp1+ sebaceous gland cells. Cell Death Dis5, e1141
Aung, A., Seo, Y. N., Lu, S., Wang, Y., Jamora, C., del Alamo, J. C., and Varghese, S. (2014) 3D traction stresses activate protease-dependent invasion of cancer cells. Biophys J107, 2528-2537
Ando, T., Xiao, W., Gao, P., Namiranian, S., Matsumoto, K., Tomimori, Y., Hong, H., Yamashita, H., Kimura, M., Kashiwakura, J., Hata, T. R., Izuhara, K., Gurish, M. F., Roers, A., Rafaels, N. M., Barnes, K. C., Jamora, C., Kawakami, Y., and Kawakami, T. (2014) Critical role for mast cell Stat5 activity in skin inflammation. Cell Rep6, 366-376
Cowburn, A. S., Takeda, N., Boutin, A. T., Kim, J. W., Sterling, J. C., Nakasaki, M., Southwood, M., Goldrath, A. W., Jamora, C., Nizet, V., Chilvers, E. R., and Johnson, R. S. (2013) HIF isoforms in the skin differentially regulate systemic arterial pressure. Proc Natl Acad Sci U S A110, 17570-17575
Bhatt, T., Rizvi, A., Batta, S. P., Kataria, S., and Jamora, C. (2013) Signaling and mechanical roles of E-cadherin. Cell Commun Adhes20, 189-199
Ando, T., Matsumoto, K., Namiranian, S., Yamashita, H., Glatthorn, H., Kimura, M., Dolan, B. R., Lee, J. J., Galli, S. J., Kawakami, Y., Jamora, C., and Kawakami, T. (2013) Mast cells are required for full expression of allergen/SEB-induced skin inflammation. J Invest Dermatol133, 2695-2705
Xu, J., Caro-Diaz, E. J., Lacoske, M. H., Hung, C. I., Jamora, C., and Theodorakis, E. A. (2012) Fusarisetin A: Scalable Total Synthesis and Related Studies. Chem Sci3, 3378-3386
Kanemaru, K., Nakamura, Y., Sato, K., Kojima, R., Takahashi, S., Yamaguchi, M., Ichinohe, M., Kiyonari, H., Shioi, G., Kabashima, K., Nakahigashi, K., Asagiri, M., Jamora, C., Yamaguchi, H., and Fukami, K. (2012) Epidermal phospholipase Cdelta1 regulates granulocyte counts and systemic interleukin-17 levels in mice. Nat Commun3, 963
Swamy, M., Jamora, C., Havran, W., and Hayday, A. (2010) Epithelial decision makers: in search of the 'epimmunome'. Nat Immunol11, 656-665
Li, C., Lasse, S., Lee, P., Nakasaki, M., Chen, S. W., Yamasaki, K., Gallo, R. L., and Jamora, C. (2010) Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8. Proc Natl Acad Sci U S A107, 22249-22254
Du, F., Nakamura, Y., Tan, T. L., Lee, P., Lee, R., Yu, B., and Jamora, C. (2010) Expression of snail in epidermal keratinocytes promotes cutaneous inflammation and hyperplasia conducive to tumor formation. Cancer Res70, 10080-10089
Baldo, C., Jamora, C., Yamanouye, N., Zorn, T. M., and Moura-da-Silva, A. M. (2010) Mechanisms of vascular damage by hemorrhagic snake venom metalloproteinases: tissue distribution and in situ hydrolysis. PLoS Negl Trop Dis4, e727
Mielgo, A., Torres, V. A., Schmid, M. C., Graf, R., Zeitlin, S. G., Lee, P., Shields, D. J., Barbero, S., Jamora, C., and Stupack, D. G. (2009) The death effector domains of caspase-8 induce terminal differentiation. PLoS One4, e7879
Lee, P., Lee, D. J., Chan, C., Chen, S. W., Ch'en, I., and Jamora, C. (2009) Dynamic expression of epidermal caspase 8 simulates a wound healing response. Nature458, 519-523
Boutin, A. T., Weidemann, A., Fu, Z., Mesropian, L., Gradin, K., Jamora, C., Wiesener, M., Eckardt, K. U., Koch, C. J., Ellies, L. G., Haddad, G., Haase, V. H., Simon, M. C., Poellinger, L., Powell, F. L., and Johnson, R. S. (2008) Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell133, 223-234
Jamora, C., Lee, P., Kocieniewski, P., Azhar, M., Hosokawa, R., Chai, Y., and Fuchs, E. (2005) A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol3, e11
Perez-Moreno, M., Jamora, C., and Fuchs, E. (2003) Sticky business: orchestrating cellular signals at adherens junctions. Cell112, 535-548
Jamora, C., DasGupta, R., Kocieniewski, P., and Fuchs, E. (2003) Links between signal transduction, transcription and adhesion in epithelial bud development. Nature422, 317-322
Hoffman, L. M., Nix, D. A., Benson, B., Boot-Hanford, R., Gustafsson, E., Jamora, C., Menzies, A. S., Goh, K. L., Jensen, C. C., Gertler, F. B., Fuchs, E., Fassler, R., and Beckerle, M. C. (2003) Targeted disruption of the murine zyxin gene. Mol Cell Biol23, 70-79
Jamora, C., and Fuchs, E. (2002) Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol4, E101-108
Jamora, C., Theodoraki, M. A., Malhotra, V., and Theodorakis, E. A. (2001) Investigation of the biological mode of action of clerocidin using whole cell assays. Bioorg Med Chem9, 1365-1370
Fuchs, E., Merrill, B. J., Jamora, C., and DasGupta, R. (2001) At the roots of a never-ending cycle. Dev Cell1, 13-25
Jamora, C., Yamanouye, N., Van Lint, J., Laudenslager, J., Vandenheede, J. R., Faulkner, D. J., and Malhotra, V. (1999) Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D. Cell98, 59-68
Jamora, C. (1999) 100 years of Golgi complexities. Trends Cell Biol9, 37-38
Jamora, C., Takizawa, P. A., Zaarour, R. F., Denesvre, C., Faulkner, D. J., and Malhotra, V. (1997) Regulation of Golgi structure through heterotrimeric G proteins. Cell91, 617-626
Jamora, C., Dennert, G., and Lee, A. S. (1996) Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. Proc Natl Acad Sci U S A93, 7690-7694
Badarinath, K., Dutta, A., Hegde, A, Pincha, N. Gund. R, C. Jamora. (2018) Interactions between epidermal keratinocytes, dendritic epidermal T-cells, hair follicle stem cells. In Skin Stem Cells, 2nd Edition. Methods in Molecular Biology (Kursad Turksen, series editor). Springer Publishers
Jamora C. (2014). Mechanisms of Wound Repair. In Stem Cells: From Basic Research to Therapy, Volume 2. (Federico Calegari and Claudia Waskow, editors). CRC Press.
National Symposium on Stem Cells and Cellular Therapy, SGPGIMS, Lucknow India (November 2022): “Regulation and Deployment of Stem Cells in the Wounded Skin”
Skin Physiology International Meeting, Vichy, France (November 2022): “Immunosenescence in Wound Healing”
University of Hyderabad, India (October 2022): “Regulation of Epithelial Stem Cells in Wounded Skin”.
Indian Academy Degree College, Bangalore, India (May 2022): “Stem cells and wound healing”
Singapore International Skin Conference (March 2022): “Regulation of antimicrobial peptides in the skin”
Rajiv Gandhi Centre for Biotechnology, Kerala, India. National Science Day Keynote Lecture (February 2022): “Stem Cells and Wound Healing”
Saveetha College of Allied Health Sciences (Department of Biomedical Sciences) (October 2021): “Stem Cells and Wound Healing”
inStem Science Setu Webinar Series (August 2021): “How does the skin heal wounds?
BMS College of Engineering for Women International Microbiology Webinar, 2020. “Harnessing the Body’s Innate Immune Defense to Combat Infection”
St. Joseph College, Department of Microbiology, Bangalore, India, 2020. “Understanding the Wound Healing Program”
IDEA 2020 Conference. Bangalore, India. “Understanding the Wound Healing Program”
Skin Immunity Workshop, Jarkarta, Indonesia 2019. “Antimicrobial peptides in the skin”
Mechano Developmental Biology Meeting, Coorg, India 2019. “Mechanical and Epigenetic Regulation of Wound Healing”
Indian Institute of Technology (IIT) – Hyderabad 2019. “Understanding the Wound Healing Program and Allied Diseases”.
Indo-Australian Symposium on Epithelial-Mesenchymal Transition. National Centre for Cell Science, Pune, India 2018. “A non-canonical signaling pathway mediating Snail-induced fibrosis”
University of Miami – Dermatology Medical Science Training Program First Annual Conference. Miami, Florida 2018. “Mast Cells and Fibrosis”
2015 – present Scientific Advisor, Aeon Biotherapeutics Inc. (Taiwan, ROC)
2013 – 2023 Coordinator (equivalent to Department Chair), Centre for Inflammation and Tissue Homeostasis, inStem.
2021 – present Member, Scientific Advisory Committee. Therapy Resistance and Stem Cell Biology Group, Advanced Centre for Treatment, Research, and Education in Cancer (ACTREC), Mumbai India
2020 –2022 Member, Governing Council of inStem 2020 –2022.
2020 – 2023 Principal Investigator (for inStem), Bangalore Life Science Cluster COVID Testing Laboratory. 2020 – pres.
2020 – 2023 Principal Investigator (for inStem), Bangalore Life Science Cluster COVID Biorepository
2019 – 2020 Nodal Officer, Office of the Principal Scientific Adviser to the Government of India, Innovation Excellence Indicators for Public Funded R&D Organizations
2020 – 2023 Lead Investigator, Indigenisation of Diagnostics (InDx) Project, Centre of Excellence for Clinical Studies supported by a grant from the Rockefeller Foundation
