Faculty at School of Natural Sciences
Animesh Samanta
Assistant Professor
School of Natural Sciences
Contact Information
- Email: [email protected]
- Number: Ext 660
Chemical Biology
Organic Fluorophore Synthesis, Nanohybrids formulation, Molecular sensing, Bio-imaging, Diagnostics, and Drug delivery and Therapeutics
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2005, B.Sc., Vidyasagar University, Midnapore College
2007, M.Sc., IIT Madras
2012, Ph.D., National University of Singapore, Dept. of Chemistry, under Prof. Young Tae Chang
05/19-Present
Assistant Professor, Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Delhi-NCR
2016-2019
Ramanujan Fellow, CSIR-NIIST, Trivandrum
2015-2016
Postdoctoral Fellow, National University of Singapore (NUS), Biomed. Eng.
2012-2015
Postdoctoral Fellow, Singapore Bioimaging Consortium (SBIC) A*STAR
2021, Core Research Grant 2021, CRG/2021/002313; Title: Unbiased Screening of Diversity Orientated Fluorescence Library to accelerate the Probe Development for Diagnostics and Environmental Analysis
2021, The young investigator research award 2021 on 6th April, Shiv Nadar University, Delhi-NCR
2016, Ramanujan Fellowship, Govt. of India, Award No. SB/S2/RJN-148/2015
2012, DST-INSPIRE Faculty Fellowship, DST, Govt. of India, Award No. IFA12-CH-87
2012, First prize Johnson & Johnson Ser. Inc. Asia Outstanding Graduate Thesis Award in Bio-tech
2006, R Padmanabhan Memorial Prize, I.I.T. Madras
2007, QUALIFIED JAM
2007, NET (JRF)
2005, GATE
2022
- Depletion Driven Assembly of Ultra-Small Metal Nanoclusters: From Kinetically Arrested Assemblies to Thermodynamically Stable, Spherical Superclusters, Bera, D.; Baruah, M.; Dehury, A.; Samanta, A.; Chaudhary, Y.; Goswami, N*, J. Phys. Chem. Lett., 2022,XXXXX, IF: 6.88.
- PET- and ICT-Based Ratiometric Probe: An Unusual Phenomenon of Morpholine-Conjugated Fluorophore for Mitochondrial pH Mapping during Mitophagy, Munan S., A., Ali, M., Yadav R., Mapa*, K., Samanta, A.*, Anal. Chem., 2022, 94, 33, 11633–11642, IF: 7.2, https://doi.org/10.1021/acs.analchem.2c02177
- An efficient PeT based fluorescent probe for mapping mitochondrial oxidative stress produced via the Nox2 pathway, Baruah M., Jana A., Ali, M., Mapa, K., Samanta, A.*, J. Mater. Chem. B, 2022,10, 2230-2237, IF: 7.57, https://doi.org/10.1039/D2TB00356B
- Activity-based fluorescent probes for sensing and imaging of Reactive Carbonyl species (RCSs), Jana A., Baruah M., Samanta, A.*, Chem. Asian J., 2022, 17, e202200044, IF: 4.85, http://dx.doi.org/10.1002/asia.202200044
- IndiFluors: A New Full-Visible Color-Tunable Donor–Acceptor–Donor (D1–A–D2) Fluorophore Family for Ratiometric pH Imaging during Mitophagy, Munan, S., Kottarathil, S., M. Joseph, M., Jana, A., Ali, M., Mapa, K., Kumar Maiti, K.*, & Samanta, A.*, ACS Sens. 2022, xx, xxx IF: 7.8, https://doi.org/10.1021/acssensors.1c02381
- An Efficient Molecular Luminophore based on Tetraphenylethylene (TPE) Enabling intracellular Detection and Therapeutic Benefits of Hydrogen Sulfide in Alzheimer’s Disease, Ramya, A, N., Joseph, M. M., Karunakaran, V., Ahammed, C. V. S., Samanta, A., Maiti K. K.*, Sens. Actuators B Chem. 2022, 355, 131118, IF: 7.46, https://doi.org/10.1016/j.snb.2021.131118
2021
- ICT based water-soluble fluorescent probe for discriminating mono and dicarbonyl species and analysis in foods, Jana, A.; Baruah, M., Munan, S., Samanta, A.*, Chem. Commun., 2021,57, 6380-6383, IF: 6.25, https://doi.org/10.1039/D1CC02600C
- A single benzene fluorescent probe for efficient formaldehyde sensing in living cells using glutathione as an amplifier, Jana A., Joseph, M. M., Munan S., Shamna K., Maiti, K. K.*, Samanta A.,* J. Photochem. Photobiol. B, 2021, 214, 112091. IF: 6.22, https://doi.org/10.1016/j.jphotobiol.2020.112091
2020
- Highly selective chemosensor for reactive carbonyl species based on simple 1,8-diaminonaphthalene, Jana A., Joseph, M. M., Munan S., Maiti, K. K.*, Samanta A.,* J. Photochem. Photobiol. B, 2020, 213, 112076, IF: 6.22, https://doi.org/10.1016/j.jphotobiol.2020.112076
- A new pentacyclic pyrylium fluorescent probe that responds to pH imbalance during apoptosis, Chakraborty S., Joseph, M. M., Varughese, S., Ghosh, S., Maiti, K. K., Samanta A.,* and Ajayaghosh A.* Chem. Sci., 2020,11, 12695-12700, IF: 9.55, https://doi.org/10.1039/D0SC02623A
2019
- A Novel NIR Probe Tracks and Treats Lung Tumor Initiating Cells by targeting HMOX2, Kim, J.J.; Lee, Y.A.;Su, D.; Lee, J.; Park, S.J.; Kim, B.; Lee, J.H.J.; Hong, S.C.; Lu, W.; Samanta A.; Kwon, H.Y.; Kim, J.Y.; Wang,Z.; Kang, N.Y.; Chang Y.T.* J. Am. Chem. Soc. 2019, 141, 14673-14686, IF: 14.3 DOI: 10.1021/jacs.9b06068
- Visualizing Alzheimer's Disease Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7, Park, S. J.,Ho, H. C., Arai, S., Samanta, A., Olivo, M., Chang Y. T.*, Scientific Report, 2019, IF: 4.5. DOI: 10.1038/s41598-019-48329-4
2018
- A Cyclometalated Ir(III) Complex as Lysosome Targeted Photodynamic Therapeutic Agent for Integrated Imaging and Therapy in Cancer Cells, Sudheesh, K. V., Jayaram, P.S., Samanta, A., Bejoymohandas, K. S., Jayashree, R. S., Ajayaghosh, A.* Chem. Eur. J., 2018, 24, 10999-11007, IF: 5.5, DOI: 10.1002/chem.201801918
- pH‐Controlled Nanoparticles Formation and Tracking of Lysosomal Zinc Ions in Cancer Cells by Fluorescent Carbazole–Bipyridine Conjugates, Sudheesh, K. V., Joseph, M. M., Philips, D. P., Samanta, A., Maiti, K. K., Ajayaghosh, A.*, Chem. Select, 2018, 3, 2416-2422, IF: 1.81. DOI: https://doi.org/10.1002/slct.201703131
- Seeing Elastin: A Near-Infrared Zwitterionic Fluorescent Probe for In Vivo Elastin Imaging, Su. D., Chai L. T., Park, S. J.,Kim, J. J., Samanta, A., Bi, R., Dinish, U.S., Olivo, M., Chang, Y. T.*, Chem, 2018, 4, 1128-1138, IF: 14.1. https://doi.org/10.1016/j.chempr.2018.02.016
2017
- Real-Time In Vivo Hepatotoxicity Monitoring Through Chromophore-Conjugated Photon-Upconverting Nanoprobes, Peng, J.; Samanta, A.; Zeng, X.; Han, S.; Wang, L.; Su, D.; Loong, D. T. B.; Kang, N. Yang.; Park, S. J.; All, A. H.; Jian, W.; Yuan, L.; Liu, X.; Chang, Y. T.* (Joint 1st Author), Angew. Chem. Int. Ed. Engl. 2017, 56, 4165–4169, IF: 12.1 (Joint first author). https://doi.org/10.1002/anie.201612020
- Gold and Hairpin DNA Functionalization of Upconversion Nanocrystals for Imaging and In Vivo Drug Delivery, Han, S.; Samanta, A.; Xie, X.; Huang, L.; Peng, J.; park, S. J.; Teh, D. B. L.; Choi, Y.; Tian, J.; Chang, Y. T.; All, A. H.; Yang, Y.; Xing, B.; Liu, X.*, Adv. Mat. 2017, 29, 1700244, IF: 21.9, https://doi.org/10.1002/adma.201700244
- Ultrasensitive NIR-SERRS Probes with Multiplexed Ratiometric Quantifcation for In Vivo Antibody Leads Validation, Kang, H.; Jeong, S.; Jo, A.; Chang, H.; Yang, J-K.; Jeong, C.; Kyeong, S.; Lee,Y. W.; Samanta, A.; Maiti, K. K.; Cha, M. G.; Kim, T.-K.; Lee, S.; Jun, B- H.; Chang, Y. T.; Chung, J.; Lee, H. Y.; Jeong, D. H.;* Lee, Y. S.* Adv. Healthcare Mat. 2017, 4, 1700870, IF: 5.5, DOI: 10.1002/adhm.201700870
2016
- Development of highly selective, sensitive and fast response upconversion luminescent platform for hydrogen sulfide detection, Peng, J.; Teoh, C. L.; Zeng, X.; Wang, L.; Xu, W.; Samanta, A.; Su, D.; Yuan, L.; Liu, X.; Chang, Y. T.*, Adv. Func. Mat., 2016, 26, 191-199, IF: 13.3, https://doi.org/10.1002/adfm.201503715
- A Diradical Approach towards BODIPY-Based Dyes with Intense Near-Infrared Absorption around l = 1100 nm, Ni, Y.; Lee, S.: Son, M.; Aratani, N.; Ishida, M.; Samanta, A.; Yamada, H.; Chang, Y. T.; Furuta, H.; Kim, D.; Wu, J.* Angew. Chem. Int. Ed. Engl. 2016, 55, 2815–2819, IF: 12.1. https://doi.org/10.1002/anie.201511151
- CEACAM6 is upregulated by H. pylori CagA and is a biomarker for early gastric cancer, Roy, R. K.; Hoppe, M. M.; Sharma, N.; Srivastava, S.; Samanta, A.; Tan, K. T.; Yang, h.; Voon, D. C.; Pang, B.; Teh, M.; Kamiya, N. M.; Hatakeyama, M.; Chang, Y. T.; Ito, Y.; Ho, K. Y.; Tan, P.; Soong, R.; Koeffler, P. H.; Yeoh, K. G.; and Jeyasekharan, A. D.* Oncotarget 2016, 7, 55290-55301, IF: 5.0, , Doi: 10.18632/oncotarget.10528
2015
- High-efficiency In Vitro and In Vivo Detection of Zn2+ by Dye-assembled Upconversion Nanoparticles, Peng, J.; Xu, W.; Chai L. T.; Han, S.; Samanta, A.; Er, J. C.; Wang, L.; Yuan, L.; Liu, X.; Chang, Y. T.* J. Am. Chem. Soc. 2015, 137, 2336–2342, IF: 14.3, https://doi.org/10.1021/ja5115248
- The Development of a Highly Photostable and Chemically Stable Zwitterionic Near-Infrared Dye for Imaging Applications, Dongdong, S.; Chai, T.; Samanta, A.; Kang, N. Y, Park, S. J.; Chang, Y. T.* Chem. Commun. 2015, 51, 3989-3992, IF: 6.3, https://doi.org/10.1039/C4CC08814J
- Development of a Thymidine Propeller Loops Parallel-Stranded G-Quadruplexes Fluorescent Probe by Library Approach, Zhang, L, Er, J. C.; Li, X.; Heng, J. J.; Samanta, A.; Chang, Y, T. * Lee, C-L. K.* Chem. Commun. 2015, 51, 7386-7389, IF: 6.3. https://doi.org/10.1039/C5CC01601K
- CDy6, a Photostable Probe for Long-Term Real-Time Visualization of Mitosis and Proliferating Cells, Jeong, Y. M; Zhai, D; Hennig , H. Samanta, A. Agrawalla, B. K; Bray, M.; Ljosa, V.; Carpenter, A.; Chang, Y. T.* Chemistry & Biology, 2015, 22, 299-307, IF: 5.7. https://doi.org/10.1016/j.chembiol.2014.11.018
- Effect of oncogene activating mutations and kinase inhibitors on amino acid metabolism of human isogenic breast cancer cells, Kim, E. S.; Samanta, A.; Cheng, H. S.; Ding, Z.; Han, W.; Toschi, L.; Chang, Y. T.*, Mol. Biosyst. 2015, 11, 3378-3386, IF: 3.5, DOI: 10.1039/c5mb00525f
- New insight of squaraine-based biocompatible surface-enhanced Raman scattering nanotag for cancer-cell imaging, Ramya A. N.; Samanta, A.; Nisha, N.; Chang, Y. T. Maiti, K. K.* (Joint 1st Author), Nanomedicine, 2015, 10, 561-571, IF: 6.3, DOI: 10.2217/nnm.14.125
2014
- A macrophase uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation, Kang, N. Y, Park, S. J.; Ang, X. W. E.; Samanta, A.; DriesseN, W. H. P.; Ntziachristos V, Vasquez, K. O. N. Peterson, J. D. Yun, S. W.; Chang, Y. T.* Chem. Commun. 2014, 50, 6589-6591, IF: 6.3. https://doi.org/10.1039/C4CC02038C
- Milk Quality Control: Instant and Quantitative Milk Fat Determination with a BODIPY Sensor-based Fluorescence Detector, Xu, W.; Bai, J.; Peng, J.; Samanta, A.; Arya, D.; Chang Y. T.* Chem. Commun. 2014, 50, 10398-10401, IF: 6.3 https://doi.org/10.1039/C4CC04670F
- Wavelength and shape dependent SERS study to develop ultrasensitive nanotags for imaging of cancer cells, Samanta, A.; Jana, S.; Das, R.; Chang, Y. T.*, RSC Advances, 2014, 4, 12415-12421, IF: 3.0 https://doi.org/10.1039/C3RA46208K
- Multiplexing SERS nanotags for the imaging of differentiated mouse embryonic stem cells (mESC) and detection of teratoma in vivo, Samanta, A.; Das, R.; Park, S. J.; Maiti, K. K.; Chang, Y. T.* , Am. J. Nucl. Med. Mol. Imaging, 2014, 4, 114-124, IF: 3.0.
- Biocompatible surface-enhanced Raman scattering nanotags for in vivo cancer detection, Samanta, A.; Jana, S.; Das, R. K., Chang, Y. T.* Nanomedicine, 2014, 9, 523-535, IF: 6.3, DOI: 10.2217/nnm.13.222
- “Orange alert”: A fluorescent detector for bisphenol A in water environments, Zhang, L.; Er, J. C.; Xu, W.; Qin, X.; Samanta, A.; Jana, S.; Lee, C-L. K.; Chang, Y. T., Anal. Chim. Acta 2014, 815, 51-56, IF: 4.5, https://doi.org/10.1016/j.aca.2014.01.038
2012
- Multiplex targeted in vivo cancer detection using sensitive near-infrared SERS nanotags, Maiti, K. K.; Dinish, U. S.; Samanta, A.; Soh, K. S.; Vendrell, M.; Yun, S. W.; Olivo, M.; Chang, Y. T.* Nano Today, 2012, 7, 85-93, IF: 17.7, https://doi.org/10.1016/j.nantod.2012.02.008
2011
- Ultrasensitive Near-Infrared Raman Reporters for SERS-based in vivo Cancer Detection, Samanta, A.; Maiti, K. K.; Soh, K. S.; Liao, X.; Vendrell, M.; Dinish, U. S.; Yun, S. W.; Bhuvaneswari, R.; Kim, H.; Rautela, S.; Chung, J.; Olivo, M.; Chang, Y. T.* Angew. Chem. Int. Ed. Engl. 2011, 50, 6089–6092, IF: 12.1 https://doi.org/10.1002/anie.201007841
- A photostable near‐infrared protein labeling dye for in vivo imaging, Samanta, A.; Vendrell, M.; Yun, S. W.; Guan, Z.; Xu, Q. H.; Chang, Y. T.*, Chem. Asian J. 2011, 6, 1353-1356, IF: 3.7, https://doi.org/10.1002/asia.201100041
- Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters Maiti K. K.; Samanta, A.; Vendrell, M.; Soh, K. S.; Olivo, M.; Chang, Y. T.*, Chem. Commun. 2011, 47, 3514-3516, IF: 6.3, https://doi.org/10.1039/C0CC05265E
- Synthesis and characterization of a cell-permeable near-infrared fluorescent deoxyglucose analogue for cancer cell imaging, Vendrell, M.; Samanta, A.; Yun, S. W.; Chang, Y. T.*, Org. Biomol. Chem. 2011, 9, 4760-4762, IF: 3.5. https://doi.org/10.1039/C1OB05519D
- Solid Phase Synthesis of Ultra-Photostable Cyanine NIR dye library, Das, R. K.; Samanta, A.; Ha, H. H.; Chang, Y. T.* RSC Advances, 2011, 1, 573-575, IF: 3.0, https://doi.org/10.1039/C1RA00498K
- Target Identification: A Challenging Step in Forward Chemical Genetics, Das, R. K.; Samanta, A.; Ghosh, K.; Zhai, D.; Xu, W.; Su, D.; Leong, C.; Chang, Y. T.* Interdiscip. Bio Central, 2011, 3, 1-16, IF: n.a. DOI: 10.4051/ibc.2011.3.1.0003
2010
- Development of photostable near-IR cyanine dyes, Samanta, A.; Vendrell, M.; Das, R.; Chang, Y. T.* Chem. Commun., 2010, 46, 7406-7408, IF: 6.3, https://doi.org/10.1039/C0CC02366C
2009
- Novel orthogonal synthesis of tagged combinatorial trazine library via Grignard reaction, Lee, J. W.; Bork, J. T. Ha, H. H.; Samanta, A.; Chang, Y. T.*, Aust. J. Chem. 2009, 62, 1000-1006, IF: 1.8. https://doi.org/10.1071/CH09153
- Synthesis of a BODIPY Library and Its Applications to the Development of Live Cell Glucagon Imaging Probe, Lee, J. S.; Kang, N. Y.; Kim, Y. K.; Samanta, A.; Feng, S.; Kim, H. K.; Vendrell, M.; Park, J. H.; Chang, Y. T.*, J. Am. Chem. Soc., 2009, 131, 10077-10082, IF: 14.3, https://doi.org/10.1021/ja9011657
- "Diversity orientated fluorescence library approach: Accelerating the probe development for Biological and Environmental Applications (Book Chapter 1)", Animesh Samanta, Subrata Munan, Anal Jana, Young Tae Chang, Wiley-VCH, 2021 (invited, under review).
- Fluorescent biomarker enhanced endoscopy for the detection of gastric cancer, Sharma, N.; Roy, R.; Hoppe, M.; Samanta, A.; Chang, Y- T.; Srivastava, S.; Ming, T.; Guan, Y. K.; Ho, K. Y.; Jeyasekharan, A.* J. Gastroentrol Hepatol. 2016/11/1, HOBOKEN 07030-5774, NJ USA, 2016, 31, 290.
- Phosphoserine aminotransferase 1 (PSAT1) as a novel anti-tumor target in hepatocellular carcinoma, Ding, Z.; Wee, K.; Kim, E-S.; Samanta, A.; Steckel, M.; Raschke, M.; Velan, S.; Chang, Y. T.; Haegebarth, A.; Ziegelbauer, K.; Gruenewald, S.; Han, W, Cancer Res. Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA, 2015, 75, 1163.
2022
- Invited Webinar on International Winter School lecture at Amirkabir University of Technology, Iran "Inorganic Nanocarriers for Delivery of Therapeutic Agents: Diagnosis and Treatment" On 21st February, 2022.
- Invited Webinar on Meet the Leader Chemistry-2 at ADAMAS University, Kolkata "Nanomaterials for diagnostics and therapeutics" On 19th February, 2022.
- Invited Webinar on Global Summit on Sustainable Science and Technology 2022 (GS3T) at Adamas University, Kolkata, "IndiFluors: New Chemical tools for Mitophagy and Reactive Oxygen Species” On 16th September 2022.
- Invited Webinar on International Chemical Biology & Molecular Imaging Conference 2022 (iCBMIc) at Adamas University, Kolkata, "IndiFluors: New Chemical tools for Mitophagy and Reactive Oxygen Species” On 19-20th August 2022.
- Invited Webinar on International Winter School lecture at Amirkabir University of Technology, Iran "Inorganic Nanocarriers for Delivery of Therapeutic Agents: Diagnosis and Treatment” On 21st February 2022.
- Invited Webinar on Meet the Leader Chemistry-2 at ADAMAS University, Kolkata "Nanomaterials for diagnostics and therapeutics” On 19th February, 2022.
2021
- Invited Webinar on Recent Advances in Materials And Nanoscience (RAMAN’21) at Ramananda college, Bishnupur "“Nanoscience in Healthcare Research” on 12th of November, 2021. (https://ramanandacollegech.wixsite.com/raman21).
2020
- Invited WEBINAR at Akal University "NANOMATERIALS FOR HEALTHCARE" 25th November 2020. https://www.youtube.com/watch?v=ZUqB1u7f7rY&t=726s
2019
- Invited Lecture, 3rd Asian Conference on Chemosensors & Imaging Probes (AsianChIP), 6-9 November, 2019.
- "Unbiased Screening of Diversity Orientated Fluorescence Library to accelerate the Probe Development for Diagnostics and Environmental Analysis" DST-SERB, Core Research Grant: CRG/2021/002313. Duration 3 years (Amount sanctioned INR 40,22,832) (PI: Animesh Samanta).
- "Low Cost Photonic device for diagnostics applications" DST-SERB, Ramanujan Fellowship: SB/S2/RJN-148/2015; for 5 years (INR 1.03 Cr. including Fellowship; Research grant 35 lakhs) Completed this project (PI: Animesh Samanta).
- Development of Photostable Near-IR Cyanine Dyes for In Vivo Imaging – Chang. Y. –T.; Samanta. A.; Vendrell. M.; Kang, N. –Y.; Maiti, K. K.; Soh, K. S.; Dinish. U. S.; Olivo. M.; International Patent Application No: PCT/SG2011/000117.; Ref: 09227N-PCT.; Docket No. 4459.1016-000.
- Licensing Technology: A Panel of Live Fluorescent Probes for the Identification of Proliferating and Potent Human Mesenchymal Stem Cells to Zenzic Labs Pte Ltd f.k.a Brilliant Research Pte Ltd.
- Guest Editor, [Chemosensors] Special Issue "A Theme Issue in Honor of Dr. Richard Horobin—Cell or Organelle Selective Fluorescent Probes: Their Design, Mechanism, Modeling and Application".
- Affiliate member of Royal Society of Chemistry.
- Life membership of Chemical Research Society of India.
- Reviewer of many journals in RSC, ACS, MDPI, and Wiley.