Faculty at School of Natural Sciences

Kamlesh Ganesh Pawar

Kamlesh Ganesh Pawar

India Alliance Early Career Fellow

School of Natural Sciences


Contact Information

Non-coding RNAs and their function, cP-RNA-seq, T4-PNK-seq, tRNA halves, miRNAs, lncRNAs, lung injury, infection.

Indian Alliance Project: https://lsci.snu.edu.in/research/projects/role-trna-derived-non-coding-r? 

 

Ph.D., Freie Universitat MVSc, NDRI

B.VSc., Mumbai Veterinary College

01/22 - Present

India Alliance Early Career Fellow, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi-NCR

2017 - 2021

Postdoctoral research fellow, Thomas Jefferson University, Philadelphia, USA

2016 - 2017

Postdoctoral research fellow, University Hospital Zurich (USZ), Zurich, Switzerland

2010 - 2011

Assistance professor, Bidar Veterinary Collage, Bidar, Karnataka

  • 2021 DBT-Wellcome Trust India Alliance Early Career Fellowship (ECF)
  • 2021 US National Science Foundation (NSF) Award for 2021 RNA Society Meeting
  • 2021 Poster Award from RNA Society for excellence in RNA research
  • 2019 Postdoctoral Travel Fellowship from Jefferson College of Life Sciences, USA
  • 2015 Selection for summer schools in Germany

a. International summer school of modern methods in infection biology at Julius Maximilians-Universität Würzburg (5 days)

b. SYNMarburg summer school at Marburg (10 days)

c. International summer school on pathogen-host interplay at ZIBI summer school, Berlin (15 days)

  • 2012 DAAD PhD Scholarship to pursue a full time PhD in Germany
  • 2012 First place in table tennis tournament held at Goethe language institute, Germany
  • 2010 Qualified the National Eligibility Test (NET) conducted by ASRB
  • 2010 Nomination of the master's thesis for Best Thesis Award at NDRI
  • 2008 Institutional Fellowship and contingency grant for master studies at NDRI
  • 2007 Selection for "All India Inter-University Badminton Tournaments"
  • 2006 Certificate of merit for the Horse Riding from Amateur Rider's Club, Mumbai

  1. Pawar K, Shigematsu M. Sharbati, Kirino Y. Infection-induced 5’-half molecules of tRNAHisGUG activate Toll-like receptor 7. PLOS Biology 18 (12), e3000982, 2020.
  2. Pawar K, Shigematsu M, Loher P, Honda S, Rigoutsos I, Kirino Y. Exploration of CCA-added RNAs revealed the expression of mitochondrial non-coding RNAs regulated by CCA-adding enzyme. RNA Biology 16(12):1817-1825, 2019.
  3. Shigematsu M*, Pawar K*, Kawamura T, Deshpande D, Kirino Y. Allergen-induced tRNA halves affect cellular focal adhesion in asthma. bioRxiv 815803; doi: https://doi.org/10.1101/815803. *equal contribution as first author, 2019.
  4. Pawar K, C. Hanisch, S. Eliseo Palma Vera, R. Einspanier, S. Sharbati. Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy. Scientific reports. 6:19416, 2016.
  5. Pawar K, J Sharbati, Einspanier R, Sharbati S. Mycobacterium bovis BCG Interferes with miR-3619-5p Control of Cathepsin S in the Process of Autophagy. Front Cell Infect Microbiol. 6:27, 2016.
  6. Pawar K and Kaul G. Toxicity of titanium oxide nanoparticles cause functionality and DNA damage in buffalo (Bubalus bubalis) sperm in vitro. Toxicol Ind Health. 30(6):520- 33, 2014. L Hoeke, J Sharbati,
  7. Pawar K, A Keller, R Einspanier, S Sharbati Intestinal Salmonella typhimurium infection leads to miR-29a induced caveolin 2 regulation. PloS one 8 (6), e67300, 2013.
  8. Pawar K and Kaul G. Toxicity of Europium Oxide Nanoparticles on the Buffalo (Bubalus bubalis) Spermatozoa DNA Damage. Advanced Science, Engineering and Medicine. 5(1):11-17, 2013.
  9. Pawar K and Kaul G. Assessment of buffalo (Bubalus bubalis) sperm DNA fragmentation using a sperm chromatin dispersion (SCD) test. Reproduction in Domestic Animals. 46(6), 964-969, 2011.

Oral presentations:

  1. miR-3619-5p mediates Cathepsin S control of autophagy in mycobacterial infection of macrophages. Tagung der DVG-Fachgruppe "Physiologie und Biochemie". Berlin, Germany (2016).
  2. Mycobacteria escape autophagy by counter regulating long non-coding RNA MEG3. International Meeting of the German Society for Cell Biology (DGZ), Cologne, Germany (2015).
  3. Poster presentations: CCA-RNA: A novel class of RNA in cancer cells. National Cancer Institute Symposium "RNA Biology 2019". NIH, Bethesda, Maryland, USA (2019).
  4. The LncRNA MEG3 regulates autophagy in mycobacterial infection in human macrophages. Noncoding genome EMBO|EMBL symposium. Heidelberg, Germany (2015).
  5. A novel approach towards finding regulatory microRNAs during phagosomal maturation in infection. FEBS EMBO, Paris, France. (2014)

  • Role of tRNA Derived Non-Coding RNAs in Acute Lung Injury (ALI), DBT-Wellcome Trust India Alliance, INR 1.7Cr, 5 Years.