Faculty at School of Natural Sciences
Pinaki Talukdar
Adjunct Professor (Visiting)
School of Natural Sciences
Contact Information
- Email: [email protected]
Supramolecular chemistry | Molecular machines | Membrane transport | Chemical biology | Water purification
The work of Professor Pinaki Talukdar focuses on developing novel supramolecular systems for chemical biology and material science applications. By leveraging noncovalent interactions, he is able to construct supramolecular structures that can be used for ion transport, water transport, molecular recognition, etc. Diverse applications of supramolecular systems are being investigated, including therapeutic agents, reverse osmosis membranes, supramolecular polymers, and others.
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2005 |
Ph.D. in Organic Chemistry, University of Geneva, Switzerland Supervisor: Prof. Stefan Matile |
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2001 |
M.S. in Chemical Sciences, Indian Institute of Science, Bangalore M.S. Project Supervisor: Prof. Goverdhan Mehta |
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1998 |
B.Sc. in Chemistry, Presidency College, University of Calcutta |
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2019 – Present |
Adjunct Professor (Visiting), Department of Chemistry, School of Natural Sciences Shiv Nadar Institution of Eminence (Deemed to be University) |
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2019 – Present |
Professor of Chemistry, Indian Institute of Science Education and Research Pune |
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2015 – 2019 |
Associate Professor of Chemistry, Indian Institute of Science Education and Research Pune |
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2009 – 2015 |
Assistant Professor of Chemistry, Indian Institute of Science Education and Research Pune |
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2007 – 2009 |
Senior Research Scientist, Institute of Life Science, Hyderabad |
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2006 – 2007 |
Senior Research Scientist, Albany Molecular Research Inc., Hyderabad |
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2005 – 2006 |
Postdoctoral Research Associate, Chemistry Department, University of Illinois at Urbana-Champaign, Supervisor: Dr. Mary S. Gin |
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2025 |
Chirantan Rasayan Sanstha (CRS) Silver Star Award |
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2025 |
C. N. R. Rao National Prize for Chemical Sciences, Chemical Research Society of India |
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2023 |
National Prize for Bio-Physical Chemistry Research for 2023, C.N.R. Rao Education Foundation |
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2019 |
Distinguished Investigator Award, Science and Engineering Research Board, Govt. of India |
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2018 |
Bronze Medal, Chemical Research Society of India |
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2016 |
National Bioscience Award for Career Development, Department of Biotechnology, Govt. of India |
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2010 |
Young Scientist Research Award, Department of Atomic Energy (DAE), Govt. of India |
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2021 |
Rahul Bajaj Chair Professor, Indian Institute of Science Education and Research Pune |
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2023 |
Fellow of the Royal Society of Chemistry (FRSC) through the ‘Leaders in the Field’ scheme |
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2024 |
JSPS Invitational Fellowship for Research in Japan (Short Term), Japan Society for the Promotion of Science |
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2025 |
Fellow of the Indian National Science Academy (INSA) |
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Life Membership |
Chemical Research Society of India (CRSI) |
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Life Membership |
Materials Research Society of India (MRSI) |
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Life Membership |
Chemical Biology Society (CBS), India |
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Life Membership |
Indian Biophysical Society (IBS), India |
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Life Membership |
Chirantan Rasayan Sanstha (CRS) |
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1. |
Photo-activation of Tolane-based Synthetic Ion Channel for Transmembrane Chloride Transport. Sandip Chattopadhayay, Kshitij V Banzal, Pinaki Talukdar,* Angew. Chem. Int. Ed. 2025, 64, e202414354. |
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2. |
Self-Assembled Hydrazide-Based Nanochannels: Efficient Water Translocation and Salt Rejection. Abhishek Mondal, Debashis Mondal, Susmita Sarkar, Umesh Shivpuje, Jagannath Mondal, Pinaki Talukdar,* Angew. Chem. Int. Ed. 2025, 64, e202415510. |
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3. |
A Halogen-Bond-Driven Artificial Chloride-Selective Channel Constructed from 5-Iodoisophthalamide-based Molecules. Rashmi Sharma, Susmita Sarkar, Sandip Chattopadhayay, Jagannath Mondal,* Pinaki Talukdar,* Angew. Chem. Int. Ed. 2024, 63, e202319919. |
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4. |
Supramolecular Barrel-Rosette Ion Channel Based on 3,5-Diaminobenzoic Acid for Cation-Anion Symport. Sandip Chattopadhayay, Anupam Ghosh, Titas Kumar Mukhopadhyay, Rashmi Sharma, Ayan Datta,* Pinaki Talukdar,* Angew. Chem. Int. Ed. 2023, 62, e202313712. |
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5. |
A Benzohydrazide-based Artificial Ion Channel that Modulates Chloride Ion Concentration in Cancer Cells and Induces Apoptosis by Disruption of Autophagy. Abhishek Mondal, Shreyada N. Save, Susmita Sarkar, Debashis Mondal, Jagannath Mondal, Shilpy Sharma, Pinaki Talukdar,* J. Am. Chem. Soc. 2023, 145, 9737–9745. |
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6. |
Selective and rapid water transportation across a self-assembled peptide-diol channel via the formation of a dual water array. Debashis Mondal, Bhupendra R. Dandekar, Manzoor Ahmad, Abhishek Mondal, Jagannath Mondal,* Pinaki Talukdar,* Chem. Sci. 2022, 13, 9614–9623. |
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7. |
A Glutathione Activatable Ion Channel Induces Apoptosis in Cancer Cells by Depleting Intracellular Glutathione Levels. Javid Ahmad Malla, Rintu M. Umesh, Saleem Yousf, Shrunal Mane, Shilpy Sharma, Mayurika Lahiri, Pinaki Talukdar,* Angew. Chem. Int. Ed. 2020, 59, 7944–7952. |
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8. |
Phototriggered Release of a Transmembrane Chloride Carrier from an o‐Nitrobenzyl‐Linked Procarrier. Swati Bansi Salunke, Javid Ahmad Malla, Pinaki Talukdar,* Angew. Chem. Int. Ed. 2019, 58, 5354–5358. |
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9. |
Chloride Transport through Supramolecular Barrel-Rosette Ion Channels: Lipophilic Control and Apoptosis-Inducing Activity. Tanmoy Saha, Amitosh Gautam, Arnab Mukherjee, Mayurika Lahiri, Pinaki Talukdar,* J. Am. Chem. Soc. 2016, 138, 16443–16451. |
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10. |
Chloride-Mediated Apoptosis-Inducing Activity of Bis(sulfonamide) Anionophores. Tanmoy Saha, Munshi Sahid Hossain, Debasis Saha, Mayurika Lahiri, Pinaki Talukdar,* J. Am. Chem. Soc. 2016, 138, 7558–7567. |
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1. |
Invited Lecture: Development of Stimuli-Responsive Artificial Ion Channels. Solvay Workshop on “The Interplay of Molecules and Membranes”. Université libre de Bruxelles, Belgium. April 28-30, 2025. |
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2. |
Award Lecture: Development of Artificial Ion Channels to Combat Cancer. 90th Anniversary General Meeting of Indian National Science Academy (INSA) at SRM Institute of Science & Technology, Kattankulathur, Chennai. December 9-10, 2024. |
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3. |
Invited Lecture: Photoport: Harnessing Light for Efficient Ion Transport Across Lipid Membranes. Chemical Science 2024: Leaders in the Field Symposium, organised by Chemical Science journal of Royal Society of Chemistry and IISER Thiruvananthapuram. December 9-11, 2024. |
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4. |
Invited Lecture: Photoassembled Ion Channels: Applications of Photoisomerization and Photocleavage Strategies for Chloride Channel Formation. Nanopore Weekly Meeting. August 26, 2024. (Online) |
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5. |
Invited Lecture: Crafting Small Molecule-Based Engineered Channels for Selective and Regulated Ion Transport and Targeting Diseases. Shiv Nadar University. July 15, 2024. |
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6. |
Invited Lecture: Crafting Small Molecule-Based Engineered Channels for Selective and Regulated Ion Transport and Targeting Diseases. Tokyo Institute of Technology (Suzukakedai Campus). June 04, 2024. |
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7. |
Invited Lecture: Crafting Small Molecule-Based Engineered Channels for Selective and Regulated Ion Transport and Targeting Diseases. Osaka University. June 12, 2024. |
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8. |
Invited Lecture: Development of Artificial Ion Transporters as Therapeutic Agents to Combat Cancer. University of Warsaw. December 15, 2023. |
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9. |
Invited Lecture: Biomimetic Artificial Ion Transport Systems: from Design to Applications. Workshop on "Biomimetic and Electroactive Membranes (BMEM 2023), Indian Institute of Technology Bombay. December 07-08, 2023. |
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10. |
Invited Lecture: Development of artificial ion channels to target cancer. 2023 Organellar Channels and Transporters Gordon Research Conference, Barcelona, Spain. August 06-11, 2023. |
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11. |
Invited Lecture: Artificial ion transport as a tool to target cancer. Asian Chemical Biology Initiative (ACBI) Meeting 2022, IISER Pune, September 14, 2022. |
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12. |
Invited Lecture: Supramolecular Channel Machinery to Target Cancer with Ions. International Symposium on Cell Surface Macromolecules 2020 (ISCSM2020), IISER Pune. February 17-20, 2020. |
- Development of Self-assembled Synthetic Water Channels as Biomimetic Membranes for Water Desalination. Funder: SERB (Ongoing)
- Development of cyclic saccharide-based synthetic chloride transporters and evaluation of their apoptosis inducing activity. Funder: DST, Under DST-RSF Scheme (Completed)
- Light-activated supramolecular ion channels for transmembrane anion transport Funder: SERB (Completed)
Oral Presentations:
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1. |
Synthetic Ion Channels for Selective Anion Transport. 10th International Symposium on Macrocyclic and Supramolecular Chemistry (10th ISMSC-2015) in Strasbourg, France. June 28 - July 02, 2015. |
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2. |
Unimolecular and Supramolecular Artificial Ion Channel Systems. German Symposium in Supramolecular Chemistry (SupraChem 2015) at Freie Universität Berlin, Germany. February 23-24, 2015. |
Poster Presentations:
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1. |
Poster Presentation: Chloride Transport through a Supramolecular Barrel-Rosette Ion Channel Leads to Apoptosis-Inducing Activity. Gordon Research Conference on Self-Assembly & Supramolecular Chemistry, Equilibrated and Non-Equilibrated Systems for Anomalous Structures and Properties. Les Diablerets, Switzerland. May 21-26, 2017. |
Scholarly Services:
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2025 – Present |
Editorial Board Member of Journal of Inclusion Phenomena and Macrocyclic Chemistry |
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2021 – Present |
Editorial Advisory Board for ACS Organic & Inorganic Au |
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2022 – Present |
Associate Editor in Chemical Biology - Frontiers in Chemistry |
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2022 |
Topic Editor on Artificial Membrane Transporters in Frontiers in Chemistry |
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2022 – Present |
Member, Technical Expert Committee (TEC) on Biomedical Engineering and Stem cells, DBT, Govt. of India |
Peer Review Service:
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Reviewer Roles: |
ACS Applied Materials & Interfaces, ACS Chemical Biology, ACS Omega, Analyst, Analytical Chemistry, Angewandte Chemie, Chemical Communications, Chemical Science, Journal of the American Chemical Society, Journal of Chemical Sciences, Langmuir, Luminescence, The Journal of Organic Chemistry, Organic and Biomolecular Chemistry, Organic Chemistry Frontiers, Research on Chemical Intermediates, RSC Advances, Sensors & Actuators: B. Chemical, etc. |