Faculty at School of Natural Sciences

Santanu Ghosh

Santanu Ghosh

Assistant Professor

School of Natural Sciences


Contact Information

Bio-active Natural Product Synthesis, Asymmetric Catalysis, New Methodology Development, Drug Discovery

  • 2015, Ph.D., Indian Institute of Science Education and Research Bhopal, Advisor: Prof. Alakesh Bisai
  • 2009, M.Sc., Vidyasagar University
  • 2007, B.Sc., Vidyasagar University

  • 01/23-Present, Assistant Professor, Department of Chemistry, School of Natural Sciences, Shiv Nadar University, Delhi-NCR
  • June 2018-November 2022: Post-doctoral Fellow, Max-Planck-Institut für Kohlenforschung, Department of Homogeneous Catalysis, Germany, Advisor: Prof. Benjamin List (Nobel Laureate 2021 in Chemistry)
  • February 2017-March 2018: Post-doctoral fellow, University of California Santa Barbara, California, USA, Advisor: Prof. Armen Zakarian
  • July 2015-December 2016: Post-doctoral fellow, Indian Institute of Science Education and Research Bhopal, India, Advisor: Prof. Alakesh Bisai

  • 2018, Max Planck Post-doctoral Fellowship
  • 2016, SERB Indo-U.S. Post-doctoral Fellowship
  • 2015, Eli Lilly Asia Outstanding Thesis Award
  • 2015, IISER Bhopal Institute Post-doctoral Fellowship
  • 2010-2015, CSIR Junior and Senior Research Fellowship

  • [20] Maji, R.; Ghosh, S.;† Grossmann, O.;† Zhang, P.; Leutzsch, M.; Tsuji, N.; List B.* “A Catalytic Asymmetric Hydrolactonization.” Am. Chem. Soc. 2023, 145, 8788−8793. [DOI: 10.1021/jacs.3c01404] (†Both authors have equally contributed)
  • [19] Ghosh, S.; Erchinger, J. E.; Maji, R.; List, B.* “Catalytic Asymmetric Spirocyclizing Diels-Alder Reactions of Enones: Stereoselective Total and Formal Syntheses of α-Chamigrene, β-Chamigrene, Laurencenone C, Colletoic Acid, and Omphalic Acid.” Am. Chem. Soc. 2022, 144, 6703–6708. [DOI: 10.1021/jacs.2c01971]
  • [18] Ghosh, S.; Das, S.; De, C. K.; Yepes, D.; Neese, F.; Bistoni, G.; Leutzsch, M.; List, B.* “Strong and Confined Acids Control Five Stereogenic Centers in Catalytic Asymmetric Diels˗Alder Reactions of Cyclohexadienones with Cyclopentadiene.” Chem. Int. Ed. 2020, 59, 12347–12351. [DOI: 10.1002/anie.202000307] [Highlighted in Synfacts]
  • [17] Gladfelder, J.; Ghosh, S.; Podunavac, M.; Cook, A. W.; Ma, Y.; Woltornist, R. A.; Keresztes, I.; Hayton, T. W.; Collum, D. B.; Zakarian, A.* “Enantioselective Alkylation of 2-Alkylpyridines Controlled by Organolithium Aggregation.” Am. Chem. Soc. 2019, 141, 15024−15028. [DOI: 10.1021/jacs.9b08659]
  • [16] Chaudhuri, S.; Ghosh, S.; Bhunia, S.; Bisai, A.* “Catalytic Asymmetric Formal Total Syntheses of (+)- and (−)-Cycloclavine.” Commun. 2018, 54, 940−943. [DOI:10.1039/C7CC09045E]
  • [15] Kumar, N.; Das, M. K.; Ghosh, S.; Bisai, A.* “Development of Catalytic Deacylative Alkylations (DaA) of 3-Acyl-2-Oxindoles: Total Synthesis of meso-Chimonanthine and Related Alkaloids” Commun. 2017, 53, 2170−2173. [DOI: 10.1039/C6CC10228J]
  • [14] Kumar, N.;† Ghosh, S.;† Bhunia, S.; Bisai, A.* “Synthesis of 2-Oxindoles via 'Transition Metal-Free' Intramolecular-Dehydrogenative-Coupling (IDC) of sp2 C-H and sp3 C-H Bonds: Scopes and Limitations” Beilstein J. Org. Chem. 2016, 12, 1153−1169. (Invited article) (†Both authors have equally contributed). [DOI:10.3762/bjoc.12.111]
  • [13] Chaudhuri, S.; Parida, A.; Ghosh, S.; Bisai, A.* “Highly Stereoselective Syntheses of Proline-Derived Vicinal Amino Alcohols Through Grignard Addition onto N-Tosylprolinal” 2016, 27, 215−220. [DOI: 10.1055/s-0035-1560802]
  • [12] Ghosh, S.;† Chaudhuri, S.;† Bisai, A.* “Catalytic Enantioselective Decarboxylative Allylations of a Mixture of Allylcarbonates and Allylesters: Total Syntheses of (−)- and (+)-Folicanthine” - Eur. J. 2015, 21, 17479−17484. (†Both authors have equally contributed) [DOI:10.1002/chem.201502878]
  • [11] Babu, N. K.; Kinthada L. K.; Ghosh, S.; Bisai, A.* “Highly chemoselective synthesis of dimeric 2-oxindoles with a C-3/C-5′ linkage via Friedel–Crafts alkylations of 2-oxindoles with 3-hydroxy-2-oxindoles” Biomol. Chem. 2015, 13, 10641−10655. [DOI: 10.1039/C5OB01670C]
  • [10] Ghosh, S.; Chaudhuri, S.; Bisai, A.* “Oxidative Dimerization of 2-Oxindoles Promoted by KOtBu-I2: Total Synthesis of (±)-Folicanthine” Lett. 2015, 17, 1373−1376. [One of the 3 Most-Read Articles in March 2015]. [DOI: 10.1021/acs.orglett.5b00032]
  • [9] Parida, A.; Sharique, M.; Kakde, B. N.; Ghosh, S.; Bisai, A* “Efficient Synthesis of [3-(2-Arylethyl)]-Cyclohexen-2-ones via Stork-Danheiser Sequence of Vinylogous Esters with Terminal Alkynes’’ Synthesis 2015, 47, 2965−2970. [DOI: 10.1055/s-0034-1380451]
  • [8] Kinthada L. K.; Ghosh, S.; Babu, N. K.; Mohd., S.; Biswas, S.; Bisai, A.* “Friedel–Crafts Alkylations of Electron-rich Aromatics with 3-Hydroxy-2-oxindoles: Scope and Limitations” Biomol. Chem. 2014, 12, 8152−8173. [DOI: 10.1039/C4OB01264J]
  • [7] Ghosh, S.; Bhunia, S.; Kakde B. N.; De, S.; Bisai, A.* “Enantioselective Construction of Vicinal All-Carbon Quaternary Centers via Catalytic Double Asymmetric Decarboxylative Allylation” Commun. 2014, 50, 2434−2437. [One of the Most-Read Articles in December 2013]. [DOI: 10.1039/C3CC49064E]
  • [6] Dey, D.; Ghosh, S.; Chopra, D.* “Quantitative Evaluation of C–H...O and C–H...pi Intermolecular Interactions in Ethyl-3-benzyl-1- methyl-2-oxoindoline-3-carboxylate and 3-Methyl-but-2-en-1-yl-1, 3-dimethyl-2-oxoindoline-3-carboxylate: Insights from PIXEL and Hirshfeld Analysis” Chem. Cryst., 2014, 44, 131. [DOI: 10.1007/s10870-014-0492-8]
  • [5] Bhunia, S.; Ghosh, S.; Dey, D.; Bisai, A.* “DDQ-Mediated Direct Intramolecular-Dehydrogenative Coupling (IDC): Expeditious Approach to the Tetracyclic Core of Ergot Alkaloids” Lett. 2013, 15, 2426−2429. [DOI: 10.1021/ol400899e]
  • [4] Kinthada, L. K.; Ghosh, S.; De, S.; Bhunia, S.; Dey, D.; Bisai, A.* “Acid-Catalyzed Reactions of 3-Hydroxy-2-oxindoles with Electron-rich Substrates: Synthesis of 2-Oxindoles with All-Carbon Quaternary Centers” Biomol. Chem. 2013, 11, 6984−6993. [DOI: 10.1039/C3OB41482E]
  • [3] Ghosh, S.; De, S.; Kakde B, N.; Bhunia, S.; Adhikary, A.; Bisai, A.* “Intramolecular Dehydrogenative Coupling of sp2 C-H and sp3 C-H Bonds: An Expeditious Route to 2-Oxindoles” Lett. 2012, 14, 5864−5867. [One of the 5 Most-Read Articles in December 2012] [DOI: 10.1021/ol302767w]
  • [2] Ghosh, S.; Kinthada, L. K.; Bhunia, S.; Bisai, A.* “Lewis-Acid Catalyzed Friedel-Crafts Alkylations of 3-Hydroxy-2-oxindoles: An Efficient Approach to the Core Structure of Azonazine” Commun. 2012, 48, 10132−10134. [DOI: 10.1039/C2CC35283D]
  • [1] De, S.; Ghosh, S.; Bhunia, S.; Sheikh J, A.; Bisai, A.* “Intramolecular Direct Dehydrohalide Coupling Promoted by KOtBu: Total Synthesis of Amaryllidaceae Alkaloids Anhydrolycorinone and Oxoassoanine” Lett. 2012, 14, 4466−4469. [DOI: 10.1021/ol3019677]