Oxidative dehydrogenation strategy for the synthesis of nitrogen heterocycles | Shiv Nadar University
Enquire Now
Apply Now
Undergraduate AdmissionsPhD Admissions Spring 2023MBA Admissions 2023MBA Information Session

Oxidative dehydrogenation strategy for the synthesis of nitrogen heterocycles

The primary objective of this present work is to develop synthetic procedures for the construction of biologically important nitrogen heterocycles such as quinazoline, benzimidazole, beta-carboline, benzothiazole by employing different oxidant in a sustainable way. The first chapter describes N-bromosuccinimide promoted synthesis of beta-carbolines and 3,4-dihydro-beta-carbolines from tetrahydro-beta-carbolines. The second chapter of this thesis involves o-iodoxybenzoic acid mediated tandem synthesis of quinazolines and dihydroquinazolines from 2-aminobenzylamine. Chapter-3 involves an oxone mediated tandem synthesis of benzimidazoles via a ring distortion strategy. The last chapter describes anhydrous cerium chloride catalyzed, 2-iodoxybenzoic acid mediated oxidative dehydrogenation of multiple heterocycles at room temperature.

Department: 
Chemistry
Year: 
2017
Student Name: 
Santanu Hati
Faculty Advisor: 

Directions