SCHOOL OF NATURAL SCIENCES
NATURAL SCIENCES
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Faculty
Department of Life Sciences
Naga Suresh Veerapu, Ph.D.
Assistant Professor
Department of Life Sciences
School of Natural Sciences
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Education:
Ph.D., All India Institutes of Medical Sciences
M.Sc., Andhra University
Professional Experience
2013 – Present: Assistant Professor, Department of Life Sciences, Shiv Nadar University, India
2011 – 2013 : Postdoctoral Associate, Liver Diseases, Mount Sinai School of Medicine, USA
2006 – 2011 : Visiting Fellow, Liver Diseases Section, NIDDK, NIH, USA.
Current grants:
IIDP-HepC Program: Developing Novel, Robust Genotype-3 Hepatitis C Virus In Vitro Culture System through Bioselection. Dept. of Biotechnology, Government of India. 2015-2018. Principal Investigator.
DST Young Scientist Scheme: Exploring Robust In Vitro Hepatitis E Genotype-1 Replication System, Ministry of Science and Technology (SERB), Government of India. 2016-2019. Principal Investigator
Research Interests
My research interests are to characterize the virus-host interactions, to hepatitis C and E. Both viruses are positive-strand RNA viruses that cause viral hepatitis the most common forms of liver disease. The high mortality rate of pregnant women with hepatitis E infection underscores the need for continued basic research. A reasonable starting point for studies of HCV and HEV-host interactions is to identify strains that have a heightened replication potential. Our research uses evolutionary biotechnology approaches and focuses on HCV gt3 and HEV genotype-1 viral strains.
Select Publications
Veerapu NS*, Park SH*, Tully DC, Allen TM. Rehermann B. Infectivity of Trace Amounts of Hepatitis C Virus That Sporadically Reappear After Successful Antiviral Therapy. Journal of Clinical Investigation. 2014, 124:3469-78. *co-first author

Park SH, Veerapu NS, Shin EC, Angélique Biancotto, J. Philip McCoy, Capone S, Folgori A, Rehermann B. Subinfectious Hepatitis C Virus Exposures Suppress T Cell Responses Against Subsequent Acute Infection. Nature Medicine, 2013, 19:1638-42.

Veerapu NS, Raghuraman S, Liang TJ, Heller T, Rehermann B. Sporadic reappearance of minute amounts of HCV RNA after successful therapy stimulates cellular immune responses. Gastroenterology, 2011; 140(2): 676-685. *listed on the cover page of Gastroenterology, Vol 140, 
No. 2.

Shin EC, Park SH, Demino M, Nascimbeni M, Mihalik K, Major M, Veerapu NS, Heller T, Feinstone SM, Rice CM, Rehermann B. Delayed induction, not impaired recruitment, of specific CD8T cells causes the late onset of acute hepatitis C. Gastroenterology, 2011:; 141(2):686-95.

Suresh N, Singh UB, Gupta C, Arora J, Rana T, Samantaray JC. Rapid detection of rifampin resistant Mycobacterium tuberculosis directly from stained sputum smears using single-tube nested polymerase chain reaction deoxyribonucleic acid sequencing. Diagnostic Microbiology and Infectious Diseases, 2007; 58(2): 217-22.

Suresh N, Arora J, Pant H, Rana T, Singh UB. Spoligotyping of Mycobacterium tuberculosis DNA from Archival Ziehl-Neelsen-stained sputum smears. Journal of Microbiological Methods, 2007; 68(2):291-5

Suresh N, Singh UB, Arora J, Pande JN, Seth P, Samantaray JC. Rapid detection of rifampicin-resistant Mycobacterium tuberculosis by in-house, reverse line blot assay. Diagnostic Microbiology and Infectious Diseases, 2006; 56(2): 133-40.

Suresh N, Singh UB, Arora J, Pant H, Seth P, Sola C, Rastogi N, Samantaray JC, Pande JN. rpoB gene sequencing and spoligotyping of multidrug-resistant Mycobacterium tuberculosis isolates from India. Infection Genetics and Evolution, 2006; 6(6): 474-83.

Arora J, Singh UB, Suresh N, Rana T, Porwal C, Kaushik A, Pande JN. Characterization of predominant Mycobacterium tuberculosis strains from different subpopulations of India. Infection Genetics and Evolution, 2009; 9(5): 832-9.

Singh UB, Arora J, Suresh N, Pant H, Rana T, Sola C, Rastogi N, Pande JN. Genetic biodiversity of Mycobacterium tuberculosis isolates from patients with pulmonary tuberculosis in India. Infection Genetics and Evolution, 2007; 7(4): 441-8.

Singh UB, Bhanu NV, Suresh VN, Arora J, Rana T, Seth P. Utility of polymerase chain reaction in diagnosis of tuberculosis from samples of bone marrow aspirate. American Journal of Tropical Medicine Hygiene, 2006; 75(5):960-3.

Bhanu NV, Singh UB, Chakraborty M, Suresh N, Arora J, Rana T, Takkar D, Seth P. Improved diagnostic value of PCR in the diagnosis of female genital tuberculosis leading to infertility. Journal of Medical Microbiology, 2005; 54:927-31.

Singh UB, Suresh N, Bhanu NV, Arora J, Pant H, Sinha S, Aggarwal RC, Singh S, Pande JN, Sola C, Rastogi N, Seth P. Predominant tuberculosis spoligotypes, Delhi, India. Emerging Infectious Diseases, 2004; 10(6): 1138-42.

Sen S, Kashyap S, Singh UB, Suresh N, Chand M, Garg SP. Intraocular tuberculosis mimicking retinoblastoma: a case report. Diagnostic Cytopathology, 2003; 28:107-9.

Patent

PCR Based Reverse Line Blot Assay for the Detection of MDR TB Isolates. Urvashi B Singh, Naga Suresh Veerapu. TB Laboratory, Microbiology Department, AIIMS, New Delhi. Submitted to the Indian Government.
National & International Recognition
Travel Fellowship to attend 17th International Conference on HCV and Related Viruses, Yokahama, Japan, 2010.
5-year Visiting Fellowship (2006-2011) from US Government, NIDDK, NIH
Indian Council of Medical Research's J.B. Srivastav Oration Award - Virology
Executive Summary
Dr. Naga Suresh Veerapu earned Ph.D. from AIIMS, New Delhi in the area of Molecular Medical Microbiology in 2005. He worked in Dr. Urvashi B Singh laboratory on rapid molecular diagnosis of MDR-TB. In 2006, he joined Dr. Rehermann’s laboratory, Liver Diseases Section, NIDDK, NIH and had worked on HCV persistence and infectious nature of persisted HCV. Before joining Shiv Nadar University Dr. Veerapu moved to Dr. Andrea Branch laboratory, MSSM, NY; along with Dr. Frances Eng, Dr. Veerapu continued working on HCV Core gene alternative translation mechanisms.
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